Monster Chase is a cooperative memory game for players 3 to 7 years old. In the game, monsters creep out from under the bed and try to surround it. Each monster is only afraid of one toy that will banish it to the closet amongst the ten that are available to be found. If the players successfully send all the monsters to the closet before they can close the circle around the bed, they win! Otherwise, the monsters are declared victorious.

In game terms, face-down cards are placed on the table with tiles then placed around these cards. To start, a card is revealed that depicts a monster and the toy it's afraid of. In turn order, each player must now find the toy that scares off this monster, with the toy being hidden in the face-down tiles. If players make three mistakes when searching for this toy, a new monster appears with a different toy needed to scare it away. Once all the monsters are out, you have only three chances to win by getting rid of all the monsters.

The rules offer different difficulty levels to adapt to player experience and/or maturity, such as one tile that shuffles the other tiles around and one tile that instantly brings out a new monster.